The raid in Homs countryside reportedly coincided with another missile attack against a military airbase near Damascus.
Local reporter Ibrahim Joudeh took to Twitter and posted a video of the missiles being shot at in the sky.
The Syrian state television report did not, however, specify who may have fired the missiles. Reports of that attack had been swirling on social media before the announcement.
Initial reports claim the raid is aimed at the T4 base, but others say it is aimed at Shyrat AB which was hit past year in the US Tomahawk attack. Reports close to the regime indicated that its defences shot down six missiles targeting the base.
A local reporter for The Arab News said Israeli warplanes were spotted in Syrian airspace just before the missiles were reported.
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Six missiles targeted the Shayrat airbase in the central province of Homs and the Syrian air defenses intercepted majority, said the report, adding that three other missiles targeted the Dumair airbase in the Dumair area in the eastern Qalamoun region north of Damascus and were all intercepted before reaching their targets.
"There is no USA military activity in that area at this time", the Pentagon's spokesperson told Reuters.
The air strikes came in response to a suspected gas attack in Douma, outside Damascus, earlier this month in which the World Health Organization has said 43 people who died suffered "symptoms consistent with exposure to highly toxic chemicals".
The recent incident follows a coordinated attack by the US, UK and France that saw over 100 missiles launched from US ships and UK Tornado fighter-bombers.