The strikes this time have been larger in scale, with more targets.
The Syrian military says it's now in control of the eastern Ghouta suburbs of Damascus.
Moscow also said it was calling an emergency session of the United Nations Security Council, where it is a permanent member, to discuss the "aggressive actions" of the U.S. and its allies.
Vassily Nebenzia, Moscow's ambassador to the United Nations, said he "cannot exclude" war between the United States and Russian Federation.
On Thursday, Russia's military said Douma has been brought under full control of the Syrian government under a Russia-mediated deal that secured the evacuation of the rebels and thousands of civilians after it was recaptured by Syrian forces.
Destiny's Child Reunited At Coachella
We don't think you're ready for Destiny Child's surprise performance at Coachella , but we're going to show you anyway! The pop songstress kicked off a highly-anticipated two-hour set with a rendition of "Lift Every Voice and Sing".
Britain's U.N. Ambassador Karen Pierce meanwhile rejected a charge by a Russian defence ministry spokesman that Britain was involved in staging a fake chemical weapons attack in Douma. "We can not take such risks", said Dvorkovich, speaking at a forum.
Russian Federation says there is no evidence of a chemical attack in Douma and has warned the United States and its allies against carrying out any military strike.
US allies have offered strong words of support for Washington but no clear military plans have yet emerged.
In a Saturday statement, the Iranian Foreign Ministry denounced the US-led coalition's attacks on Syria as "a flagrant breach of global laws" and "a violation of Syria's right to national sovereignty and territorial integrity".
UN Secretary-General Antonio Guterres told the Security Council Friday that "there is no military solution to the conflict".
The US, UK and France said they launched air strikes against Syrian chemical sites after obtaining evidence that a chemical weapon was used by President Bashar Assad's government.