Rose first spoke out about her alleged ordeal to the New York Times newspaper, who allegedly obtained legal documents stating that the $100,000 payout agreed between Weisntein and Rose was "not to be construed as an admission" by Weinstein, but meant to "avoid litigation and buy peace".
She has also been calling out Hollywood stars that she considers to be hypocritical by name.
The show will chronicle her experience as a champion for survivors of sexual violence.
The first two hours will air January 30 with four more episodes due out in the spring.
Meryl Streep has said she "didn't know" about Weinstein's alleged behaviour and she was "hurt" to be "attacked" by McGowan. But she added that she faces the sale of her house to pay "legal bills fighting off the monster".
"My father said I was born with my fist up".
But she says she's not aiming to be a poster woman for the movement.
Moon-walking astronaut John Young dies at 87
Young had been due to command a 1986 flight that was cancelled after the explosion of the shuttle Challenger earlier that year. Nasa said Mr Young was the only agency astronaut to go into space as part of the Gemini, Apollo and space shuttle programmes.
"The narrative that has been run by your peers for 20 years has been erroneous, has been a lie and has been cruel", she said. "As I ready my book, Brave, I realised I wanted to show how we can heal through art even when being hounded by evil", said McGowan. And "it's not important for me to be seen as anything; I'm happy to live a private existence".
"And when that new day finally dawns, it will be because of a lot of magnificent women, many of whom are right here in this room tonight, and some pretty phenomenal men, fighting hard to make sure that they become the leaders who take us to the time when nobody ever has to say "Me too" again". Executive producer Andrea Metz said McGowan didn't tell them the details of those, but just said, "Trust me".
What does she hope to accomplish with the new series?
E!, the network that brought us such gems as Keeping Up With The Kardashians, announced this week that they have picked up Citizen Rose which will begin as a two-part documentary based on Rose McGowan's activism.
"I don't want to hear about the silence of me". She claims she was set up on the charges of drug possession that led to an arrest in November and was briefly suspended from Twitter in October following tweets accusing Ben Affleck of lying about his knowledge of Weinstein's behavior.
"I'm comfortable working there", McGowan said.